From: The relationship of insulin resistance and diabetes to tau PET SUVR in middle-aged to older adults
 | HOMA-IR sample | Diabetic Status sample | ||||
---|---|---|---|---|---|---|
b (SE)b | p | 95% CI | b (SE)b | p | 95% CI | |
(a) | ||||||
Age (years) | .001 (.002) | .42 | −.002 to .005 | .004 (.002) | .02 | .001 to .007 |
Sex (0=female) | −.06 (.03) | .04 | −.11 to −.003 | −.02 (.03) | .56 | −.07 to .04 |
Cognitive status (0=unimpaired)c | .20 (.13) | .13 | −.06 to .46 | .22 (.09) | .02 | .04 to .41 |
Amyloid PET DVR | .68 (.12) | <.001 | .45 to .91 | .79 (.10) | <.001 | .60 to .99 |
HOMA2-IR | .02 (.02) | .23 | −.01 to .05 | -- | -- | -- |
Cohort (WRAP=0) | -- | -- | -- | .08 (.03) | .004 | .03 to .14 |
Diabetic status (0=nondiabetic) | -- | -- | -- | .04 (.04) | .32 | -.04 to .13 |
(b) | ||||||
Age (years) | .001 (.002) | .39 | −.002 to .005 | .004 (.002) | .04 | .0002 to .007 |
Sex (0=female) | −.06 (.03) | .04 | −.11 to −.003 | −.03 (.03) | .30 | −.08 to .03 |
Cognitive status (0=unimpaired)c | .19 (.13) | .16 | .07 to .45 | .23 (.09) | .01 | .05 to .41 |
Amyloid PET DVR (centered)d | .69 (.13) | <.001 | .44 to .93 | .75 (.11) | <.001 | .54 to .97 |
HOMA2-IR (centered)e | .03 (.03) | .42 | −.03 to.09 | -- | -- | -- |
HOMA2-IR × amyloid PET DVR | .10 (.23) | .68 | −.36 to .55 | -- | -- | -- |
Cohort (WRAP=0) | -- | -- | -- | .08 (.03) | .008 | .02 to .13 |
Diabetic status (0=nondiabetic) | -- | -- | -- | .06 (.05) | .26 | -.04 to .16 |
Diabetic status × amyloid PET DVR | -- | -- | -- | .36 (.26) | .17 | −.16 to .88 |