Alzheimer's Research & Therapy

Table 2 Univariable and multivariable logistic regression analysis results for predictors of lobar ICH development

From: The effects of imaging markers on clinical trajectory in cerebral amyloid angiopathy: a longitudinal study in a memory clinic

	Univariable		Multivariable
	HR (CI)^a	p-value	HR (CI)^a	p-value
Age	1.02 (0.93, 1.12)	0.719	NA
Hypertension	0.24 (0.05, 1.16)	0.076	0.23 (0.04, 1.33)	0.101
Hyperlipidemia	0.27 (0.04, 2.09)	0.211	NA
Smoking	0.49 (0.06, 3.97)	0.503	NA
Anticoagulant use	7.89 (0.75, 83.5)	0.086	7.06 (0.18, 272.92)	0.294
Presence of cSS	12 (2.47, 58.25)	0.002	6.45 (1.21, 34.5)	0.029
APOE2	5.33 (1.4, 20.25)	0.014	2.55 (0.52, 12.38)	0.246
APOE4	0.14 (0.02, 1.09)	0.061	0.23 (0.02, 2.29)	0.21
ln(1 + lobar CMBs)	0.97 (0.58, 1.61)	0.911	NA
Previous lobar ICH	9.3 (2.48, 34.9)	0.001	4.9 (1.09, 21.92)	0.038
Severe CSO-EPVS	0.46 (0.06, 3.73)	0.468	NA
Multi-spot WMH	1.03 (0.26, 4.09)	0.970	NA
Severe WMH	0.86 (0.34, 2.17)	0.746	NA

Independent variables which were significant with p-value < 0.2 in the univariable logistic regression analysis were subsequently included in the multivariable logistic regression analysis
Abbreviations: HR, hazard ratio; CI, confidence interval; NA, not applicable; cSS, cortical superficial siderosis; CMBs, cerebral microbleeds; ICH, intracerebral hemorrhage, WMH, white matter hyperintensity

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ISSN: 1758-9193

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