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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Early tau detection in flortaucipir images: validation in autopsy-confirmed data and implications for disease progression

Fig. 5

A The average SUVR surface map of Q3 (Eτ−/ADsignature−) subjects, showing a lack of elevated flortaucipir signal in the entire cortex. B The average SUVR surface map of Q2 (Eτ+/ADsignature–) subjects. There is an elevated flortaucipir signal primarily in the regions of Eτ VOI region with the exception of the left middle temporal gyrus. C The average SUVR surface map of Q1 (Eτ+/ADsignature+) subjects. Widespread elevation of flortaucipir signal across the entire cortex with the exception of postcentral, precentral, and paracentral gyri and anterior cingulate. D–F Surface maps showing the percentages of subjects that are tau positive for all FreeSurfer regions in Q3 (Eτ−/ADsignature−), Q2 (Eτ+/ADsignature–), and Q1 (Eτ+/ADsignature+), respectively

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Alzheimer's Research & Therapy

ISSN: 1758-9193