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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Early tau detection in flortaucipir images: validation in autopsy-confirmed data and implications for disease progression

Fig. 3

A Boxplots showing the 18-month change in Eτ VOI SUVR across the quadrants. The 18-month change in Eτ VOI SUVR was significantly different between subjects in Q2 (or Q1) and Q3. B Boxplots showing the 18-month change in ADsignature VOI SUVR across the quadrants. The 18-month change in ADsignature VOI SUVR was significantly different across the quadrants (Q1 > Q2 > Q3). C Boxplots showing the 18-month change in cortical thickness across the quadrants. The 18-month change in cortical thickness was significantly different across the quadrants (Q1 < Q2 < Q3). D Boxplot showing the 18-month change in MMSE across the quadrants. The 18-month change in MMSE was significantly different across quadrants (Q1 < Q2 < Q3). A total of 109 subjects from the treatment arm of the solanezumab trial were excluded from these analyses. Note: the N’s are different in the above boxplots for flortaucipir change, thickness, and MMSE due to the availability of the data

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