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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Altered metabolic connectivity within the limbic cortico-striato-thalamo-cortical circuit in presymptomatic and symptomatic behavioral variant frontotemporal dementia

Fig. 3

Metabolic connectivity within the limbic CSTC circuits in asymptomatic MAPT mutation carriers. A Connectivity weights in asymptomatic mutation carriers compared with noncarriers. Asymptomatic mutation carriers showed the decreased fronto-striatal connectivity and compensatory increased striato-thalamo and thalamo-cortical connection within limbic CSTC circuits. B Connectomes projected onto a 3D brain template. Enhanced metabolic connections are represented by red lines, and weakened metabolic connections are represented by blue lines. Abbreviations: vmPFC, ventromedial prefrontal cortex; ACC, anterior cingulate cortex

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Alzheimer's Research & Therapy

ISSN: 1758-9193