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Table 3 Logistic regression analysis between the PSWEs and MCI in patients with OSA (n=275)

From: Paroxysmal slow wave events are associated with cognitive impairment in patients with obstructive sleep apnea

 

Model 0

Model 1

OR (95%CIs)

P value

OR (95%CIs)

P value

Duration ratios of PSWEs at C3/M2 in stage R

1.067 (1.020–1.117)

0.005

1.058 (1.009–1.109)

0.019

Duration ratios of PSWEs at C4/M1 in stage R

1.090 (1.038–1.145)

0.001

1.091 (1.034–1.151)

0.001

Duration ratios of PSWEs at F3/M2 in stage R

1.084 (1.038–1.132)

<0.001

1.084 (1.033–1.137)

0.001

Duration ratios of PSWEs at F4/M1 in stage R

1.078 (1.033–1.124)

<0.001

1.074 (1.026–1.124)

0.002

Duration ratios of PSWEs at O1/M2 in stage R

1.062 (1.030–1.096)

<0.001

1.063 (1.027–1.099)

<0.001

Duration ratios of PSWEs at O2/M1 in stage R

1.060 (1.027–1.094)

<0.001

1.058 (1.022–1.095)

0.001

Duration ratios of PSWEs at T3/M2 in stage R

1.108 (1.052–1.166)

<0.001

1.109 (1.048–1.174)

<0.001

Duration ratios of PSWEs at T4/M1 in stage R

1.102 (1.049–1.158)

<0.001

1.105 (1.046–1.166)

<0.001

  1. Model 0: unadjusted
  2. Model 1: adjusted for age, sex, education, vascular risk factors (e.g., hypertension, diabetes mellitus, hyperlipidemia), HAMD scores, Aβ42, and AHI
  3. Abbreviations: PSWE paroxysmal slow wave event, MCI mild cognitive impairment, OSA obstructive sleep apnea, OR odds ratio, CIs confidence interval, HAMD Hamilton Depression Scale, Aβ amyloid-β, AHI apnea-hypopnea index, R rapid eye movement