Table 1 Demographic and cognitive characteristics of the sample
From: Effects of non-modifiable risk factors of Alzheimer’s disease on intracortical myelin content
Controls | APOE4 | Controls | FH | Controls | APOE4+FH | Controls | APOE4 or FH | |
|---|---|---|---|---|---|---|---|---|
Age | 67.8 ± 6.1 | 67.8 ± 6.1 | 67.2 ± 4.8 | 67.2 ± 4.8 | 67.5 ± 5.4 | 67.5 ± 5.4 | 66.9 ± 5.5 | 66.9 ± 5.5 |
Sex (F/M) | 28/22 | 28/22 | 30/22 | 30/22 | 16/19 | 16/19 | 58/44 | 58/44 |
Education years | 10.4 ± 5.1 | 10.4 ± 5.1 | 10.8 ± 5 | 10.8 ± 5 | 10.4 ± 4.8 | 10.4 ± 4.8 | 10.6 ± 5 | 10.6 ± 5 |
ApoE4 | 0 | 50 | 0 | 0 | 0 | 35 | 0 | 50 |
FH | 0 | 0 | 0 | 52 | 0 | 35 | 0 | 52 |
CDR | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MMSE | 28.6 ± 1.1 | 29.1 ± 1.1 | 29 ± 1 | 29.1 ± 1 | 28.9 ± 1.1 | 28.8 ± 1.2 | 28.8 ± 1.1 | 28.9 ± 1 |
Memory Binding Test | ||||||||
Total free recall | 17.3 ± 4.2 | 17.1 ± 4.1 | 17.8 ± 4.7 | 17.1 ± 3.2 | 19 ± 4.2 | 18.2 ± 5.2 | 17.9 ± 4.4 | 17.2 ± 4 |
Total delayed free recall | 18.2 ± 3.6 | 18 ± 5.8 | 17.2 ± 4.7 | 17.3 ± 5.1 | 19.1 ± 3.6 | 20 ± 6.7 | 18 ± 4.1 | 17.6 ± 5.6 |
Total delayed paired recall | 26.5 ± 3.3 | 26.1 ± 4 | 24.4 ± 5.5 | 23.9 ± 3.5 | 27.2 ± 3.1 | 26.4 ± 5.7 | 25.7 ± 4.4 | 24 ± 4 |
Boston Naming Test | 12.6 ± 2.1 | 12.4 ± 2.4 | 12.7 ± 1.8 | 12.9 ± 1.8 | 12.9 ± 1.6 | 12.4 ± 1.2 | 12.7 ± 1.9 | 12.7 ± 2 |
Trail Making Test-A (seconds) | 43.9 ± 15.6 | 43.6 ± 21.3 | 38.1 ± 11.1 | 41.3 ± 20.2 | 41.1 ± 15.8 | 40.2 ± 15.6 | 41.2 ± 14.2 | 41.4 ± 19.6 |
Trail Making Test-B (seconds) | 122 ± 61.8 | 120.1 ± 65.8 | 115.2 ± 65.5 | 112.2 ± 55.3 | 110.4 ± 51.5 | 106.5 ± 57.1 | 117 ± 60.5 | 114 ± 60 |
Tower of London (seconds) | 364.2 ± 147.4 | 366.4 ± 113.3 | 367.8 ± 124.3 | 371.2 ± 149.6 | 377.1 ± 119.6 | 382 ± 127.3 | 369.2 ± 130.8 | 373 ± 133.5 |