Fig. 2

Moderating effects of A history of hypertension, B current SBP state, and C current DBP state on the relationship between global Aβ and IT tau deposition. ^a Each line and statistical values represent the relationship between cerebral Aβ and tau stratified by each blood pressure marker (e.g., history of hypertension, current SBP state, or current DBP state), based on the repeated linear regression model for tau deposition using global Aβ SUVR as independent variable with adjusting for age, sex, apolipoprotein E ε4 positivity, and the vascular risk score. Shaded regions demonstrate the 95% confidence interval for each regression line. ^b The p-values are from the generalized regression models including interaction term of each blood pressure marker and global Aβ SUVR, as well as each blood pressure marker, global Aβ SUVR, age, sex, apolipoprotein E ε4 positivity, and the vascular risk score. Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure; Aβ, β-amyloid; IT, inferior temporal; SUVR, standardized uptake value ratio