Table 1 Baseline sociodemographic and cognitive profile of patients and controls

Age

72 ± 6

72 ± 6

71 ± 10

.904

Sex (% female)

50%

55%

57%

.910

Education

11 ± 5

9 ± 4

9 ± 4

.105

MMSE

29 ± 2

21 ± 2^e

22 ± 4^e

<.001

Left hippocampus (mm³)

3724 ± 339

2892 ± 433^e

2916 ± 684^e

<.001

Right hippocampus (mm³)

3794 ± 326

2951 ± 451^e

3079 ± 708^e

<.001

 RAVLT—immediate

46 ± 7 (33-65)

20 ± 7^e (6-33)

21 ± 7^e (12-39)

< .001

 RAVLT—recall

10 ± 2 (4-14)

1.1 ± 1.5^e (0-5)

2.4 ± 2.6^e (0-8)

< .001

 Episodic memory

13 ± 3 (9-21)

2.4 ± 2.2^e,a (0-10)

3.9 ± 3.8^e (0-14)

< .001

 PAL

34 ± 16 (8-64)

166 ± 28^e (104-204)

146 ± 54^e,a (22-217)

< .001

 ROCF—recall

15 ± 4 (9-26)

2.3 ± 3.2^e,b (0-9)

5.2 ± 4.6^e (0-17)

< .001

 Backward digit span

4 ± 1 (0-5)

2.6 ± 1.9 (0-5)

1.8 ± 2.0^e (0-5)

0.002

 Clock test

12 ± 1 (8-13)

5. ± 3.4^e (0-12)

7.4 ± 3.3^e (3-12)

< .001

 ROCF—copy

30 ± 4 (22-36)

22 ± 10^e,b (0-36)

20 ± 9^e (3-32)

< .001

 TMT-A

46 ± 10 (26-68)

120 ± 85^e,b (40-328)

134 ± 94^e (43-443)

< .001

 TMT-B

129 ± 46 (60-232)

387 ± 194^e,c (85-733)

267 ± 127^e,d (121-531)

< .001

 Phonemic fluency test

35 ± 8 (23-52)

24 ± 10^e (4-40)

13 ± 8^e,f (1-28)

< .001

 Semantic fluency test

40 ± 6 (29-51)

19 ± 8^e (7-33)

16 ± 8^e (6-36)

< .001

 Token test

34 ± 2 (30-37)

28 ± 5^e (17-33)

25 ± 6^e (12-34)

< .001

 RMET

20 ± 3 (14-26)

16 ± 4^e (9-25)

12 ± 4^e,f (5-20)

< .001

 EK-60F

47 ± 5 (38-54)

39 ± 8^e (23-50)

27 ± 10^e,f (10-47)

< .001