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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired individuals

Fig. 1

Tau368/t-tau is decreased in symptomatic AD. Baseline comparisons of CSF concentrations of p-tau181, p-tau217, tau368/T-tau, and T-tau in all diagnostic groups. Young individuals are not included in graphs for illustrative purposes but were included in statistical analyses. AD, Alzheimer’s disease; CU, cognitively unimpaired; MCI, mild cognitive impairment; P-tau181/217, phosphorylated tau 181/217; T-tau, total tau; CSF, cerebrospinal fluid. All P-values are derived from the Kruskal-Wallis test, adjusted for false discovery rate (FDR) using the Benjamini-Hochberg method. Tau368/t-tau, p-tau181, T-tau (n = 125), CSF p-tau217 (n = 116). *P < 0.05; ** P < 0.01; *** P < 0.001; **** P < 0.0001

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Alzheimer's Research & Therapy

ISSN: 1758-9193