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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Leading mediators of sex differences in the incidence of dementia in community-dwelling adults in the UK Biobank: a retrospective cohort study

Fig. 3

Mediators for sex differences in the incidence of young-onset dementia. Dementia diagnosed <65 years of age was categorized as young-onset dementia. Cox proportional hazards regression models were used to estimate the potential mediation effects of 133 individual factors on the association between sex and incidence of young-onset dementia. HR adjusted for mediator shows whether the association between sex and dementia was attenuated by the mediator (criterion 4). Results for the test of the other three criteria are shown in Tables 1 and S4 (criterion 1), Fig. 1 (criterion 2), and Table S7 (criterion 3)

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