Total | CN | MCI | AD | |||||
---|---|---|---|---|---|---|---|---|
β (95% CI) | p value | β (95% CI) | p value | β (95% CI) | p value | β (95% CI) | p value | |
Baseline | ||||||||
ADAS-Cog 13 | 0.086 (0.044, 0.127) | <0.001* | 0.009 (−0.033, 0.050) | 0.677 | 0.060 (0.012, 0.107) | 0.014* | 0.042 (−0.063, 0.146) | 0.432 |
MMSE | −0.161 (−0.205, −0.116) | <0.001* | −0.035 (−0.072, 0.002) | 0.063 | −0.151 (−0.201, −0.101) | <0.001* | −0.190 (−0.314, −0.065) | 0.003* |
ADNI-MEM | −0.093 (−0.133, −0.053) | <0.001* | −0.053 (−0.107, 0.001) | 0.053 | −0.060 (−0.112, −0.008) | 0.023* | −0.020 (−0.092, 0.052) | 0.585 |
ADNI-EF | −0.124 (−0.170, −0.077) | <0.001* | −0.128 (−0.193, −0.062) | <0.001* | −0.134 (−0.197, −0.071) | <0.001* | 0.074 (−0.036, 0.185) | 0.187 |
LME model | ||||||||
ADAS-Cog 13 | 0.060 (0.026, 0.094) | 0.001* | 0.025 (0.002, 0.048) | 0.032* | 0.094 (0.046, 0.142) | <0.001* | 0.015 (−0.164, 0.194) | 0.870 |
MMSE | −0.069 (−0.108, −0.030) | 0.001* | −0.054 (−0.081, −0.026) | <0.001* | −0.106 (−0.169, −0.043) | 0.001* | 0.287 (0.014, 0.559) | 0.039* |
ADNI-MEM | −0.058 (−0.090, −0.026 ) | <0.001* | −0.073 (−0.109, −0.037) | <0.001* | −0.043 (−0.092, 0.006) | 0.085 | 0.018 (−0.126, 0.162) | 0.805 |
ADNI-EF | −0.048 (−0.083, −0.012) | 0.009* | −0.042 (−0.079, −0.006) | 0.023* | −0.020 (−0.075, 0.035) | 0.473 | −0.088 (−0.308, 0.132) | 0.432 |