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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Associations of MRI-visible perivascular spaces with longitudinal cognitive decline across the Alzheimer’s disease spectrum

Fig. 3

Changes in longitudinal cognitive performance by level of CSO-PVS. A Cognitive performance among different levels of CSO-PVS groups based on the linear mixed-effects model adjusting for age, sex, education, apo ɛ4, hypertension, diabetes, hyperlipidemia, coronary heart disease, atrial fibrillation, smoking, WMH volume, hippocampus volume, and intracranial volume. B–E Trajectories of estimated cognitive performance in ADAS-Cog 13, MMSE, ADNI-MEM, and ADNI-EF by level of CSO-PVS. ADAS-Cog 13 13-item Alzheimer’s Disease Assessment Scale-cognitive subscale, MMSE Mini-Mental State Examination, ADNI-MEM ADNI memory composite score, ADNI-EF ADNI executive function score, ADNI Alzheimer’s Disease Neuroimaging Initiative

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Alzheimer's Research & Therapy

ISSN: 1758-9193