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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: Proteomic profiling of circulating plasma exosomes reveals novel biomarkers of Alzheimer’s disease

Fig. 4

Establishment of diagnostic panel for Alzheimer’s disease. A Receiver operating characteristic (ROC) curve analyses of the six-protein panel. B ROC analyses of 12 individual exosomal protein. The six proteins included in the panel are in bold. AUC, area under the curve; A0A0G2JRQ6, Ig-like domain-containing protein; C1QC, complement C1q subcomponent subunit C; CO9, complement component C9; GP1BB, platelet glycoprotein Ib beta chain; RSU1, Ras suppressor protein 1; ADA10, disintegrin and metalloproteinase domain 10 (ADAM10); CFAH, complement factor H; KVD30, immunoglobulin kappa variable 2D-30; A2MG, alpha-2-macroglobulin; A1AG2, alpha-1-acid glycoprotein 2; IGHA1, immunoglobulin heavy constant alpha 1; HV428, immunoglobulin heavy variable 4-28. P < 0.001 (A) or 0.01 (B)

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