Fig. 1
From: Proteomic profiling of circulating plasma exosomes reveals novel biomarkers of Alzheimer’s disease
Confirmation of exosomes by transmission electron microscopy (TEM), Western blot, CD9, CD63, and CD81. A Plasma samples contained vesicles of typical exosomes morphology (black arrow) under TEM from an AD patient. Scale bar = 100 nm. B Western blot analysis of Alix, a common exosome surface marker, expression in the exosome samples. Supernates served as the negative control. C–E Measurement of CD9 (C), CD63 (D), and CD81 (E) in exosomes. AD, Alzheimer’s disease; NS, no significance