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Table 6 Symptom domain causing caregivers most distress: matching status and regression analysis for caregiver–physician discordance

From: Treatment needs of dementia with Lewy bodies according to patients, caregivers, and physicians: a cross-sectional, observational, questionnaire-based study in Japan

Between caregiver and physician

Symptom domain that causes the caregiver most distress

Univariate LR analysis

Multivariate LR: input significant variables with variable increasing method (likelihood ratio)

Concordance (n = 93)

Discordance (n = 90)

OR

95% CI

p value

OR

95% CI

p value

Patient-side factor

 Autonomic dysfunction

n.e.

  

  None

63 (67.7)

45 (50.0)

1.000

ref

    

  Yes

30 (32.3)

45 (50.0)

2.100

1.153–3.826

0.015

   

Caregiver-side factors

 Patient’s most inconvenient symptom domain that the caregiver selected

   

  Cognitive impairment

29 (31.2)

26 (28.9)

2.152

0.868–5.335

0.098

2.152

0.868–5.335

0.098

  Parkinsonism

24 (25.8)

10 (11.1)

1.000

ref

 

1.000

ref

 

  Psychiatric symptoms

37 (39.8)

20 (22.2)

1.297

0.519–3.244

0.578

1.297

0.519–3.244

0.578

  Eating behavior-related problems

0 (0.0)

5 (5.6)

n.c.

  

n.c.

  

  Sleep-related disorders

1 (1.1)

13 (14.4)

31.200

3.585–271.515

0.002

31.200

3.585–271.515

0.002

  Autonomic dysfunction

2 (2.2)

16 (17.8)

19.200

3.707–99.445

<0.001

19.200

3.707–99.445

<0.001

  Sensory disorders

0 (0.0)

0 (0.0)

     

Physician-side factors

        

 Institute

     

n.e.

  

  University hospital

48 (51.6)

32 (35.6)

1.000

ref

    

  Non-university hospital

14 (15.1)

21 (23.3)

2.250

1.000–5.062

0.050

   

  Clinic

31 (33.3)

37 (41.1)

1.790

0.931–3.443

0.081

   
  1. Abbreviations: CI confidence interval, LR logistic regression, n.c. not calculated, n.e. not evaluable, OR odds ratio, ref reference