From: Continuity of care (COC) and amyloid-β PET scan: the CARE-IDEAS study
Variable | Overall | Elevated | Not elevated | p-value |
---|---|---|---|---|
N | 1171 | 798 | 373 | |
Continuity of care change | ||||
Pre-scan, mean (SD) | 0.15 (0.10) | 0.16 (0.10) | 0.15 (0.10) | .38 |
Post-scan, mean (SD) | 0.16 (0.11) | 0.16 (0.10) | 0.15 (0.11) | .07 |
Change score, mean (SD) | 0.00 (0.11) | 0.00 (0.11) | -0.00 (0.11) | .23 |
Patient characteristics | ||||
Age, mean (SD) | 75.17 (5.35) | 75.60 (5.30) | 74.27 (5.35) | < .001 |
Male | 720 (61.5%) | 480 (60.2%) | 240 (64.3%) | .17 |
Non-Hispanic white | 1099 (93.9%) | 750 (94.0%) | 349 (93.6%) | .78 |
Education | .11 | |||
High school graduate or less | 176 (15.0%) | 131 (16.4%) | 45 (12.1%) | |
Some college | 297 (25.4%) | 190 (23.8%) | 107 (28.7%) | |
Bachelor’s degree | 292 (24.9%) | 204 (25.6%) | 88 (23.6%) | |
Graduate degree | 406 (34.7%) | 273 (34.2%) | 133 (35.7%) | |
Bachelors degree or higher | 698 (59.6%) | 477 (59.8%) | 221 (59.2%) | .86 |
Cognitive functioning (TICS-M), Mean (SD) | 20.59 (6.12) | 19.72 (6.19) | 22.47 (5.54) | < .001 |
Patient medical history | ||||
Chronic kidney disease | 37 (3.2%) | 24 (3.0%) | 13 (3.5%) | .66 |
Hypertension | 611 (52.2%) | 397 (49.7%) | 214 (57.4%) | .01 |
Atrial fibrillation | 114 (9.7%) | 74 (9.3%) | 40 (10.7%) | .44 |
Ischemic heart disease | 131 (11.2%) | 93 (11.7%) | 38 (10.2%) | .46 |
Chronic obstructive pulmonary disease | 33 (2.8%) | 18 (2.3%) | 15 (4.0%) | .09 |
Diabetes | 163 (13.9%) | 102 (12.8%) | 61 (16.4%) | .10 |
Active depression | 221 (18.9%) | 136 (17.0%) | 85 (22.8%) | .02 |
Prior history of stroke or TIA | 117 (10.0%) | 75 (9.4%) | 42 (11.3%) | .32 |
Congestive heart failure | 27 (2.3%) | 16 (2.0%) | 11 (2.9%) | .32 |
Multiple sclerosis | * | * | * | .13 |
Parkinsons | 20–30 (1.7–2.6%) | 14 (1.8%) | * | .30 |
Traumatic brain injury | 66 (5.6%) | 45 (5.6%) | 21 (5.6%) | .99 |
Bipolar affective disorder | 17 (1.5%) | * | * | .02 |
History of acute myocardial infarction | 49 (4.2%) | 31 (3.9%) | 18 (4.8%) | .45 |
Dyslipidemia | 554 (47.3%) | 371 (46.5%) | 183 (49.1%) | .41 |
Epilepsy or seizure disorder | 29 (2.5%) | 18 (2.3%) | 11 (2.9%) | .48 |
Patient uses or has used tobacco | 220 (18.8%) | 136 (17.0%) | 84 (22.5%) | .03 |
Charlson Comorbidity Index, mean (SD) | 2.80 (2.32) | 2.66 (2.22) | 3.09 (2.48) | .01 |