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Table 5 Results of the mixed models’ intention to treat analyses serum concentrations 6 months after the start of the intervention (T1)

From: The effects of a moderate physical activity intervention on physical fitness and cognition in healthy elderly with low levels of physical activity: a randomized controlled trial

Outcome

Intervention group

N = 64

Control group

N = 30

Model A

N = 94

  

Model B

N = 87

  

Serum concentrations

Mean (sd)

Mean (sd)

B (95% CI)

P value

d

B (95% CI)

P value

d

IGF-I

 Baseline

13.71 (4.48)

14.16 (4.37)

      

 6 months

14.58 (4.97)

14.47 (4.15)

0.23 (− 0.27 to 0.74)

.36

.05

0.21 (− 0.33 to 0.76)

.45

.05

Insulin

 Baseline

49.91 (33.74)

54.62 (37.49)

      

 6 months

43.55 (36.30)

46.18 (21.79)

0.88 (− 3.50 to 5.26)

.69

.03

1.44 (− 3.29 to 6.20)

.55

.04

Total cholesterol

 Baseline

5.34 (1.17)

5.29 (1.11)

      

 6 months

5.40 (1.17)

5.33 (1.02)

0.02 (− 0.08 to 0.12)

.70

.02

0.02 (− 0.09 to 0.13)

.69

.02

HDL-cholesterol

 Baseline

1.43 (0.44)

1.43 (0.36)

      

 6 months

1.45 (0.45)

1.48 (0.36)

 − 0.01 (− 0.05 to 0.02)

.46

.02

 − 0.01 (− 0.05 to 0.03)

.62

.02

Triglycerides

 Baseline

1.52 (1.04)

1.62 (0.94)

      

 6 months

1.51 (0.88)

1.55 (0.85)

0.02 (− 0.08 to 0.12)

.67

.02

0.02 (− 0.09 to 0.13)

.68

.02

  1. Model A: adjusted for y at baseline, age, and sex. Model B: adjusted for y at baseline, age, sex, education, and ApoE-ε4 carrier status. PA Physical activity as measured in daily number of steps taken, ADL Activities of daily living, IGF-I Insulin-like growth factor 1, HDL High-density lipoprotein, d Cohen’s d