Fig. 2
From: Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s disease
Plasma p-tau181 associates with amyloid and tau CSF biomarkers. A Plasma p-tau181 was higher in CSF Aβ+ (n = 92) compared to Aβ− participants (n =179). B Plasma p-tau181 was positively associated with CSF Aβ42/Aβ40 ratio overall and after stratifying participants according to CSF Aβ+ (orange circles), as well as in Aβ− participants (blue circles). C Plasma p-tau181 was significantly associated with CSF p-tau181 overall and again in both Aβ+ and Aβ− participants. Raw data are presented as mean ± SD (A) or plotted with the 95% confidence band of the best-fit line with Pearson correlation coefficient r, and β estimates and p-value from linear regression models with age and sex as covariates (B and C). n = 92 (CSF Aβ+) and n = 179 (CSF Aβ−)