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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Multi-platform proteomic analysis of Alzheimer’s disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome

Fig. 2

Depth and overlap of proteomic coverage by platform in CSF and plasma. A, B Number and overlap of proteins measured by TMT-MS in depleted fluid, Olink 1196, and SomaScan 7000 platforms in CSF (left) and plasma (right) from n=36 subjects. The threshold for inclusion was measurement in at least 9 subjects (or missing values <75%). CSF measurements on the SomaScan 7000 platform underwent signal-to-noise filtering (Additional file 1: Supplementary Figure 1) prior to subsequent analyses. B Number and overlap of proteins measured in CSF and plasma within each proteomic platform

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Alzheimer's Research & Therapy

ISSN: 1758-9193