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Table 2 Participant demographics and clinical findings of the subgroups

From: Development and clinical validation of CT-based regional modified Centiloid method for amyloid PET

 

G(−)R(−)

G(−)R(+)

G(+)Str(−)

G(+)Str(+)

N

815

243

85

1102

Age (years)

68.1±11.7

70.7±9.4

73.7±7.2

70.1±9.3

Gender (F) (N, %)

437 (53.6)

128 (52.7)

60 (70.6)

635 (57.6)

APOE4 carriers (N, %)

110 (14.1)

69 (29.4)

28 (34.6)

636 (59.1)

SVLT delayed recall, mean ± SD

5±3.2

3.8±3.1

3.4±3.4

1.4±2.2

MMSE, mean ± SD

27±3.5

25.9±4.5

25.4±4.5

22.3±5.5

CDR-SOB, mean ± SD

1.5±2

2±3

2.4±3

3.9±3.2

NC/aMCI/ADD, N

414/318/83

95/115/33

26/38/21

92/462/548

FBB/FMM, N

331/484

95/148

41/44

575/527

  1. ADD Alzheimer’s disease dementia, aMCI amnestic mild cognitive impairment, APOE-ε4 apolipoprotein E ε4 allele, CDR-SOB Clinical Dementia Rating Scale Sum of Boxes, CN cognitive normal, F female, FBB18F-florbetaben, FMM18F-flutemetamol, G(−)R(−)global (−) and regional (−) Aβ rdcCL scales, G(−)R(+)global (−) and regional (+) Aβ rdcCL scales, G(+)Str(−)global (+) and striatal (−) Aβ rdcCL scales, G(+)Str(+)global (+) and striatal (+) Aβ rdcCL scales, MMSE Mini-Mental State Examination, aMCI amnestic mild cognitive impairment, SVLT Seoul Verbal Learning Test