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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Development and clinical validation of CT-based regional modified Centiloid method for amyloid PET

Fig. 1

Overview of the processing pipeline for regional Centiloid in CT-based and MRI-based methods. a Construction of a brain CT template. b Normalization of MRI and PET images onto the MNI-152 template. c Normalization of HU-corrected CT and PET images on a generated CT template. d1 The MRI-based method created global CTX VOIs for target regions in common for FMM and FBB PET. d2 The CT-based method created global CTX VOIs for target regions common in FMM and FBB PET. e1 Definition of MRI-based regional VOIs in AAL. e2 Definition of CT-based regional VOIs in AAL. f1 Equations for direct conversion of MRI-based rdcSUVRs into rdcCLs globally and in six regions (frontal, PC, parietal, striatum, occipital, and temporal). f2 Equations for direct conversion of CT-based rdcSUVRs into rdcCLs globally and in six regions

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