Skip to main content

Table 4 Summary of baseline characteristics and plasma biomarkers in dementia with Lewy bodies and corticobasal syndrome groups according to CSF amyloid (A+/–) status

From: Diagnostic value of plasma p-tau181, NfL, and GFAP in a clinical setting cohort of prevalent neurodegenerative dementias

 

DLB

CBS

A+ (n = 17)

A− (n = 31)

p value

A+ (n = 14)

A− (n = 15)

p value

Age, years

73.4 (6.3)

73.6 (7.1)

0.937

71.4 (8.0)

71.3 (6.6)

0.973

Sex (female)

7 (38.9%)

7 (22.6%)

0.326

7 (50.0%)

11 (73.3%)

0.263

MMSE, /30

19.2 (6.3)

25.1 (3.5)

< 0.001

23.6 (6.8)

25.1 (4.1)

0.829

NfL (pg/mL)

29.3 (17.1–29.3)

20.4 (14.6–35.5)

0.129

24.0 (16.4–53.1)

27.9 (21.6–53.3)

0.477

p-tau181 (pg/mL)

2.5 (1.9–3.5)

1 (0.7–1.8)

< 0.001

2.0 (1.0–3.2)

1.0 (0.7–1.3)

0.004

GFAP (pg/mL)

485.1 (380.9–705.3)

242.7 (211.1–417.2)

< 0.001

380.7 (325.3–642.9)

225.5 (178.8–302.9)

0.007

  1. Age is expressed as mean (SD), while biomarker data are presented as median (IQR)