Fig. 2

Visualization of group-level rQPPs of 4-month-old TgF344-AD rats (Tg) and wild-type littermates (WT). Results of the one-sample t-test (FDR p < 0.05, minimum cluster size 10 voxels) of QPP-DMLN (A) and QPP-LCN (C) visualized on the study-specific 3D template, demonstrating rQPPs for each experimental group. The T-maps represent statistically significant higher (red-yellow)/lower (blue-green) BOLD activity relative to the global mean BOLD signal (p < 0.05, FDR corrected). B Regional outlines of coronal slices of the Paxinos atlas overlaid on the T-map of QPP-DMLN⁺ of the WT. OFC orbitofrontal cortex, FrA frontal association cortex, MC motor cortices, SS somatosensory cortices, Cg cingulate cortex, PrL prelimbic cortex, IL infralimbic cortex, Ins insular cortex, nAcc nucleus accumbens, CPu caudate putamen, BFB basal forebrain, Pir piriform cortex, VC visual cortices, RSC retrosplenial cortex, Au auditory cortex