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Table 2 Aβ positivity based on body composition

From: Gender-specific relationship between thigh muscle and fat mass and brain amyloid-β positivity

 

Males

Females

 

OR (95%CI)a

p

OR (95%CI)a

p

p for interaction by genderb

Muscle

LASMI

0.49 (0.16–1.40)

0.192

0.27 (0.08–0.83)

0.031

0.810

Fat

GFFP

0.84 (0.73–0.95)

0.008

0.98 (0.89–1.10)

0.870

0.075

  1. Abbreviations: Aβ amyloid, OR odds ratio, BMI body mass index, LASMI lower extremity muscle mass, GFFP gluteofemoral fat percentage, NC normal cognition, MCI mild cognitive impairment
  2. aAdjusted OR for Aβ positivity was obtained by the logistic regression analysis with LASMI and GFFP together as predictors after controlling for age, APOE4 genotype, and cognitive stage (NC and MCI)
  3. bp for interaction was estimated by the logistic regression analysis including LASMI, GFFP and gender together as main effects and gender*LASMI and gender*GFFP as interaction effects after controlling for age, APOE4 genotype, and cognitive stage (NC and MCI)
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Alzheimer's Research & Therapy

ISSN: 1758-9193