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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Eicosanoid lipidome activation in post-mortem brain tissues of individuals with APOE4 and Alzheimer’s dementia

Fig. 2

Dysregulation of bioactive lipids in the Alzheimer’s disease dementia brain evidenced by lower levels of ω-3: ω-6 fatty acids and pro-resolving lipid mediator NPD1. * p < 0.05, ** p < 0.01, *** p < 0.001; two-tailed Student’s t test. Abbreviations: AA, arachidonic acid; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; DPA, docosapentaenoic acid; NPD1, neuroprotectin D1. Samples per group: NCI male 3/3 (N=6), NCI male 3/4 (N=4), NCI female 3/3 (N=6), NCI female 3/4 (N=5), AD male 3/3 (N=7), AD male 3/4 (N=3), AD female 3/3 (N=5), AD female 3/4 (N=6)

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