Domain/Variable | Typical | LP | HS | ||||||
---|---|---|---|---|---|---|---|---|---|
OR | 95%CI | PÂ value | OR | 95%CI | PÂ value | OR | 95%CI | PÂ value | |
MMSE | 0.96 | (0.85–1.09) | 0.514 | 0.82 | (0.69–0.96) | 0.015* | 1.02 | (0.90–1.15) | 0.750 |
MoCA | 0.92 | (0.80–1.06) | 0.259 | 0.76 | (0.61–0.94) | 0.014* | 1.04 | (0.92–1.19) | 0.486 |
CDR-SB | 1.27 | (0.84–1.91) | 0.254 | 1.59 | (0.93–2.71) | 0.086 | 0.77 | (0.46–1.27) | 0.317 |
Orientation | 0.75 | (0.33–1.69) | 0.492 | 0.18 | (0.05–0.70) | 0.013* | 1.17 | (0.60–2.30) | 0.640 |
Attention | 0.69 | (0.34–1.41) | 0.307 | 0.15 | (0.04–0.52) | 0.003** | 1.07 | (0.55–2.07) | 0.838 |
STM (registration) | 0.61 | (0.27–1.36) | 0.225 | 0.26 | (0.10–0.70) | 0.007** | 1.07 | (0.57–2.01) | 0.823 |
STM (recall) | 0.977 | (0.51–1.86) | 0.944 | 0.47 | (0.17–1.28) | 0.141 | 1.12 | (0.61–2.04) | 0.704 |
Language | 0.62 | (0.29–1.30) | 0.207 | 0.21 | (0.07–0.66) | 0.008** | 0.97 | (0.48–1.99) | 0.948 |
Visual execution | 0.68 | (0.33–1.39) | 0.288 | 0.12 | (0.03–0.54) | 0.006** | 0.77 | (0.40–1.51) | 0.456 |
CMB | 0.98 | (0.87–1.10) | 0.806 | 0.88 | (0.69–1.12) | 0.297 | 0.96 | (0.83–1.11) | 0.590 |
Lacune | 1.01 | (0.75–1.34 | 0.961 | 1.04 | (0.75–1.44) | 0.819 | 1.24 | (0.93–1.68) | 0.147 |
Periventricular WMH | 2.62 | (1.23–5.57) | 0.012* | 2.06 | (0.85–4.97) | 0.108 | 1.22 | (0.63–2.33) | 0.549 |
Deep WMH | 1.65 | (0.93–2.96 | 0.089 | 1.18 | (0.61–2.30) | 0.630 | 1.17 | (0.68–2.00) | 0.555 |
WMH burden | 1.11 | (0.94–1.32) | 0.244 | 1.14 | (0.93–1.40) | 0.200 | 0.994 | (0.82–1.20) | 0.947 |
BG PVSE | 1.03 | (0.57–1.87) | 0.914 | 0.99 | (0.49–1.99) | 0.988 | 0.74 | (0.39–1.37) | 0.340 |
CSO PVSE | 1.45 | (0.84–2.50) | 0.182 | 1.24 | (0.65–2.40) | 0.516 | 1.13 | (0.67–1.89) | 0.635 |
PVSE burden | 1.25 | (0.86–1.80) | 0.237 | 1.02 | (0.70–1.47) | 0.924 | 1.03 | (0.72–1.47) | 0.850 |
Global SVD score | 1.67 | (1.11–2.52) | 0.009** | 1.16 | (0.75–1.79) | 0.502 | 1.23 | (0.85–1.78) | 0.269 |
CAA-SVD score | 1.53 | (0.79–2.95) | 0.204 | 1.14 | (0.56–2.33) | 0.767 | 1.09 | (0.63–1.90) | 0.761 |
HA-SVD score | 1.93 | (1.10–3.52) | 0.034* | 2.57 | (1.23–5.37) | 0.012* | 3.30 | (1.58–6.85) | 0.001** |