Fig. 2From: Cumulative effect of simvastatin, l-arginine, and tetrahydrobiopterin on cerebral blood flow and cognitive function in Alzheimer’s diseaseTime-course of relative cerebral blood flow (rCBF) and Mini-Mental State Exam (MMSE) in all subjects. A After initiation of treatment, rCBF values significantly increased by weeks 8 and 16 in both the limbic system (red) and the selected cortical areas (black) when compared to the respective baseline values. B A modest increase was seen in the MMSE scores from baseline to 8 and 16 weeks. Data are mean ± standard error mean (SEM).*P<0.05, **P<0.01Back to article page