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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Higher levels of myelin are associated with higher resistance against tau pathology in Alzheimer’s disease

Fig. 3

Interaction between functional connectivity and MWF in fiber-tracts on covariance in a tau-PET score change. Regression plots illustrating covariance in tau-PET change as a function of both functional connectivity and MWF in fiber-tracts (binarized by median spit) in the controls (CN Aβ − /Tau − ; left column) and AD spectrum (Aβ + participants; right column) groups of the ADNI (A) and BioFINDER-1 (B) cohorts. Red line is the regression line for participants with values < median MWF, and the blue regression line is for participants with values > median MWF. For the statistical analyses, MWF was used as a continuous measure and was stratified to high and low only for illustrational purposes. MWF, myelin water fraction

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Alzheimer's Research & Therapy

ISSN: 1758-9193