Table 1 Baseline characteristics of UKB participants by dementia status (N = 375,894)
No incident dementia (N = 370,603) | Incident ACD (N = 5291) | Incident AD (N = 2301) | Incident VD (N = 1249) | |
|---|---|---|---|---|
Age, years | 57.22 (7.98) | 64.35 (4.75) | 64.75 (4.21) | 64.81 (4.27) |
Female, n (%) | 203,123 (54.81) | 2452 (46.34) | 1186 (51.54) | 501 (40.11) |
ApoE ε4 carriers, n (%) | 89,731 (24.21) | 2374 (44.87) | 1240 (53.89) | 525 (42.03) |
Higher education, n (%) | 130,207 (35.13) | 1336 (25.25) | 555 (24.12) | 260 (20.82) |
Ethnicity_White, n (%) | 349,469 (94.30) | 5003 (94.56) | 2199 (95.57) | 1179 (94.40) |
BMI, kg/m2 | 27.69 (4.91) | 27.92 (5.05) | 27.40 (4.77) | 28.68 (5.23) |
Townsend deprivation score | -1.24 (3.12) | -0.82 (3.37) | -1.02 (3.28) | -0.66 (3.46) |
Smoking | ||||
Never, n (%) | 194,964 (52.61) | 2363 (44.66) | 1080 (46.94) | 505 (40.43) |
Previous, n (%) | 132,625 (35.79) | 2266 (42.83) | 979 (42.55) | 572 (45.80) |
Current, n (%) | 40,753 (11.00) | 597 (11.28) | 213 (9.26) | 152 (12.17) |
Alcohol consumption | ||||
Never, n (%) | 17,008 (4.59) | 382 (7.22) | 177 (7.69) | 85 (6.81) |
Previous, n (%) | 14,526 (3.92) | 399 (7.54) | 149 (6.48) | 118 (9.45) |
Current, n (%) | 337,832 (91.16) | 4471 (84.50) | 1960 (85.18) | 1037 (83.03) |
Immune-mediated diseases | ||||
None, n (%) | 313,216 (84.52) | 4089 (77.28) | 1835 (79.75) | 909 (72.78) |
Any, n (%) | 57,387 (15.48) | 1202 (22.72) | 466 (20.25) | 340 (27.22) |