Skip to main content
Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation

Fig. 5

ROC curves for Aβ− vs. Aβ+ by logistic regression with single and bivariate models. Logistic regression receiver operating characteristic (ROC) analysis with leave-10-out cross-validation for single marker (blue lines) and bivariate models (including the ApoE4 allele frequency, black lines) for the Aβ42/Aβ40 ratio measured A on Elecsys in plasma without pre-analytical workup, B on Elecsys with pre-analytical Aβ immunoprecipitation (IP-eluate), and C on Meso Scale Discovery (MSD) V-PLEX Aβ panel 1 (6E10) assay with pre-analytical Aβ IP (IP-eluate). Aβ, amyloid-β; Aβ+, Aβ-positive: CSF Aβ42/40 ≤ 0.050; Aβ−, Aβ-negative: CSF Aβ42/40 > 0.050

Back to article page