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Table 3 In sex-specific meta-analysis of the blood samples in ADNI and AIBL datasets, the top 10 most significant DMRs associated with Alzheimer’s disease diagnosis identified by comb-p software at 5% Sidak adjusted P-values. CpG direction indicates hypermethylation (+) or hypomethylation (−) in AD subjects for each CpG located within the DMR, based on effect estimate in meta-analysis. Annotations include nearby genes based on GREAT and Illumina gene annotations. Highlighted in red are promoter regions of the genes mapped by the DMRs

From: Distinct sex-specific DNA methylation differences in Alzheimer’s disease

  1. Abbreviation: DMR differentially methylated region