Table 4 Associations between change in amyloid burden and cognitive test performance
From: Longitudinal change in ATN biomarkers in cognitively normal individuals
| Â | Baseline | Longitudinal | ||||
|---|---|---|---|---|---|---|
Positive-negative | Negative-positive | Positive-positive | Positive-negative | Negative-positive | Positive-positive | |
VAT-A | 0.20 (0.30) | 0.16 (0.21) | 0.05 (0.16) | 0.01 (0.11) | 0.03 (0.05) | 0.01 (0.04) |
RAVLT immediate | 3.24 (3.36) | 0.65 (2.40) | − 2.28 (1.88) | − 0.11 (0.88) | 0.04 (0.36) | − 1.40 (0.32)* |
RAVLT delayed | 0.88 (1.18) | 0.55 (0.85) | − 0.96 (0.66) | − 0.03 (0.30) | 0.05 (0.12) | − 0.51 (0.10)* |
Animal fluency | 3.48 (2.13) | 1.42 (1.51) | 0.79 (1.18) | 0.71 (0.57) | − 0.05 (0.23) | − 0.23 (0.21) |
TMT-A | 0.01 (0.11) | 0.13 (0.08) | 0.05 (0.06) | 0.03 (0.04) | − 0.04 (0.02) | − 0.01 (0.02) |
TMT-B | 0.04 (0.13) | 0.10 (0.10) | − 0.07 (0.08) | 0.01 (0.03) | − 0.02 (0.01) | − 0.02 (0.01)* |
Stroop I | 0.05 (0.07) | 0.06 (0.05) | 0.01 (0.04) | 0.01 (0.02) | − 0.03 (0.01)* | − 0.01 (0.01) |
Stroop II | 0.06 (0.07) | 0.00 (0.05) | 0.04 (0.04) | 0.00 (0.02) | − 0.02 (0.01) | − 0.02 (0.01) |
Stroop III | 0.12 (0.09) | 0.01 (0.06) | 0.02 (0.05) | − 0.01 (0.02) | − 0.03 (0.01)* | − 0.02 (0.01)* |
MMSE | − 0.23 (0.48) | 0.06 (0.34) | − 0.29 (0.26) | − 0.14 (0.18) | 0.01 (0.11) | − 0.06 (0.08) |