Skip to main content

Table 3 Associations with baseline amyloid burden and amyloid accumulation rate

From: Longitudinal change in ATN biomarkers in cognitively normal individuals

  Baseline Longitudinal
Model 1 Model 2 Model 1 Model 2
Age 0.02 (0.01) 0.00 (0.01) 0.00 (0.00) 0.00 (0.00)
Sex 0.04 (0.22) − 0.04 (0.20) 0.05 (0.03) 0.02 (0.03)
Education 0.23 (0.11)* 0.15 (0.10) 0.00 (0.02) − 0.00 (0.02)
Baseline MMSE − 0.05 (0.10) − 0.09 (0.08) 0.01 (0.01) 0.01 (0.01)
APOE ε4 carrier 0.83 (0.20)* 0.85 (0.21)* 0.11 (0.03)* 0.10 (0.03)*
  1. Data shown are beta (SE) as estimated by linear mixed models. Outcome was [18F]florbetapir over time in a composite region of interest. Models included the variable of interest, time, and their interaction as predictors. In model 1, each variable was investigated as predictor individually. In model 2, all variables were included simultaneously. Baseline estimates represent the association between the predictor and baseline BPND, longitudinal estimates represent the association of the interaction between predictor and time and reflect the slope of BPND. * p <0.05