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Table 1 Demographic, imaging, and clinical characteristics of the study participants

From: Subjective cognitive decline and anxious/depressive symptoms during the COVID-19 pandemic: what is the role of stress perception, stress resilience, and β-amyloid?

 

Overall

With SCD

Without SCD

Variable

N = 250

N = 70

N = 180

Age, years

63.5 (4.8)

63.9 (4.3)

63.3 (4.9)

Female,n(%)

153 (61.2)

43 (61.4)

110 (61.1)

Family history of sporadic AD,n(%)a

197 (89.1)

53 (75.7)

144 (80)

Caucasian,n(%)

248 (99.2)

68 (97.1)

180 (100)

Education, years

13.3 (3.5)

13.8 (3.4)

13.1 (3.5)

-positive (≥ 12CL),n(%)b

26 (12.7)

7 (10)

19 (10.6)

SCD-Q, MyCog scoresc

4.1 (4.4)

8.2 (4.5)

2.5 (3.1)

Pre-confinement HADS total scores

6.6 (4.8)

8.3 (5.1)

6 (4.5)

Confinement HADS total scores

8.1 (5.9)

9.4 (6.1)

7.6 (5.7)

PSS scoresd

16.1 (8.6)

18 (9.1)

15.4 (8.3)

BRS scorese

3.2 (0.4)

3.1 (0.3)

3.2 (0.4)

Change in HADS from pre-confinement to confinement

1.5 (5.8)

1.1 (5.2)

1.6 (5.9)

Currently diagnosed/under treatment for anxiety/depression,n(%)f

26 (10.4)

9 (12.9)

17 (9.4)

Seeking medical help due to the self-perceived decline in cognition

22 (8.8)

22 (31.4)

  1. Data are presented as mean (standard deviation) unless otherwise indicated
  2. Abbreviations: AD Alzheimer’s disease, SCD subjective cognitive decline, amyloid-beta, CL Centiloid, SCD-Q Subjective Cognitive Decline Questionnaire, HADS Hospital Anxiety and Depression Scale, PSS Perceived Stress Scale, BRS Brief Resilience Scale
  3. aOverall N = 221
  4. bOverall N = 205
  5. cOverall N = 246
  6. dOverall N = 238
  7. eOverall N = 238
  8. fOverall N = 248