Table 2 Baseline demographic and clinical characteristics of the discrepant/overlapping group
From: Tau levels are higher in objective subtle cognitive decline but not subjective memory complaint
SMC−/Obj-SCD− | SMC+/Obj-SCD− | SMC−/Obj-SCD+ | SMC+/Obj-SCD+ | F or χ2 | p | |
|---|---|---|---|---|---|---|
N | 57 | 116 | 20 | 43 | ||
Age, mean (SD) | 70.10 (5.51) | 71.14 (6.86) | 69.72 (5.94) | 71.42 (5.56) | F = 0.69 | 0.560 |
Education, mean (SD) | 17.16 (2.02) | 16.64 (2.20) | 16.90 (2.38) | 17.02 (2.39) | F = 0.82 | 0.486 |
Female/woman, % | 63.2% | 57.8% | 50.0% | 51.2% | χ2 = 1.91 | 0.592 |
Race, % | χ2 = 11.64 | 0.475 | ||||
American Indian/Alaska Native | 1.8% | 0.0% | 0.0% | 0.0% | ||
Asian | 0.0% | 1.7% | 5.0% | 2.3% | ||
Black | 0.0% | 3.4% | 5.0% | 4.7% | ||
White | 98.2% | 90.5% | 90.0% | 90.7% | ||
More than one | 0.0% | 4.3% | 0.0% | 2.3% | ||
Ethnicity, % | χ2 = 6.37 | 0.383 | ||||
Hispanic/Latino | 0.0% | 4.3% | 0.0% | 0.0% | ||
Non-Hispanic/non-Latino | 100.0% | 94.8% | 100.0% | 100.0% | ||
Unknown | 0.0% | 0.9% | 0.0% | 0.0% | ||
Pulse pressure, mean (SD) | 56.23 (12.80) | 55.03 (16.29) | 59.55 (20.38) | 53.37 (15.61) | F = 0.77 | 0.512 |
APOE ε4 carrier, % | 29.8% | 40.5% | 30.0% | 34.9% | χ2 = 2.31 | 0.511 |
GDS, mean (SD) | 0.39 (0.68)ac | 0.87 (1.16)d | 0.45 (0.69)a | 1.09 (1.43)bd | F = 4.52 | 0.004 |
CCI, mean (SD) | 13.47 (1.20)ac | 21.89 (6.45)abd | 13.80 (1.32)ac | 24.51 (7.89)bcd | F = 45.90 | < 0.001 |
PACC, mean (SD) | 1.39 (1.99)abc | 0.43 (2.47)ad | − 0.71 (3.16)d | − 1.72 (3.15)cd | F = 12.67 | < 0.001 |
Tau PET, mean (SD) | 1.42 (0.13) | 1.42 (0.13) | 1.49 (0.28) | 1.45 (0.13) | F = 1.61 | 0.187 |
Aβ PETe, mean (SD) | 17.01 (27.30) | 24.00 (31.18) | 25.47 (30.69) | 21.21 (32.60) | F = 0.77 | 0.512 |
Aβ PET positivity, % | 26.3% | 37.9% | 40.0% | 33.3% | F = 2.59 | 0.460 |