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Table 2 Baseline demographic and clinical characteristics of the discrepant/overlapping group

From: Tau levels are higher in objective subtle cognitive decline but not subjective memory complaint

  SMC−/Obj-SCD− SMC+/Obj-SCD− SMC−/Obj-SCD+ SMC+/Obj-SCD+ F or χ2 p
N 57 116 20 43   
Age, mean (SD) 70.10 (5.51) 71.14 (6.86) 69.72 (5.94) 71.42 (5.56) F = 0.69 0.560
Education, mean (SD) 17.16 (2.02) 16.64 (2.20) 16.90 (2.38) 17.02 (2.39) F = 0.82 0.486
Female/woman, % 63.2% 57.8% 50.0% 51.2% χ2 = 1.91 0.592
Race, %      χ2 = 11.64 0.475
 American Indian/Alaska Native 1.8% 0.0% 0.0% 0.0%   
 Asian 0.0% 1.7% 5.0% 2.3%   
 Black 0.0% 3.4% 5.0% 4.7%   
 White 98.2% 90.5% 90.0% 90.7%   
 More than one 0.0% 4.3% 0.0% 2.3%   
Ethnicity, %      χ2 = 6.37 0.383
 Hispanic/Latino 0.0% 4.3% 0.0% 0.0%   
 Non-Hispanic/non-Latino 100.0% 94.8% 100.0% 100.0%   
 Unknown 0.0% 0.9% 0.0% 0.0%   
Pulse pressure, mean (SD) 56.23 (12.80) 55.03 (16.29) 59.55 (20.38) 53.37 (15.61) F = 0.77 0.512
APOE ε4 carrier, % 29.8% 40.5% 30.0% 34.9% χ2 = 2.31 0.511
GDS, mean (SD) 0.39 (0.68)ac 0.87 (1.16)d 0.45 (0.69)a 1.09 (1.43)bd F = 4.52 0.004
CCI, mean (SD) 13.47 (1.20)ac 21.89 (6.45)abd 13.80 (1.32)ac 24.51 (7.89)bcd F = 45.90 < 0.001
PACC, mean (SD) 1.39 (1.99)abc 0.43 (2.47)ad − 0.71 (3.16)d − 1.72 (3.15)cd F = 12.67 < 0.001
Tau PET, mean (SD) 1.42 (0.13) 1.42 (0.13) 1.49 (0.28) 1.45 (0.13) F = 1.61 0.187
Aβ PETe, mean (SD) 17.01 (27.30) 24.00 (31.18) 25.47 (30.69) 21.21 (32.60) F = 0.77 0.512
Aβ PET positivity, % 26.3% 37.9% 40.0% 33.3% F = 2.59 0.460
  1. SMC subjective memory complaint, Obj-SCD objective subtle cognitive decline, APOE apolipoprotein E, GDS Geriatric Depression Scale, CCI Cognitive Change Index, PACC Modified Preclinical Alzheimer Cognitive Composite, Tau PET Braak III/IV SUVR, Aβ PET β-amyloid cortical SUVR in centiloids, F statistic reported for one-way ANOVAs, χ2 statistic report for chi-square tests
  2. aSignificantly different from SMC+/Obj-SCD+
  3. bSignificantly different from SMC−/Obj-SCD+
  4. cSignificantly different from SMC+/Obj-SCD−
  5. dSignificantly different from SMC−/Obj-SCD−
  6. e1 SMC+/Obj-SCD+ participant is missing Aβ PET data