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Table 4 Percent amyloid-beta and tau accumulation over 1 year and p-values assessing significant accumulation over time

From: Evaluation of tau deposition using 18F-PI-2620 PET in MCI and early AD subjects—a MissionAD tau sub-study

 

Region

Percent SUVR change

p

Amyloid-beta

Frontal

0.46 ± 6.68 %

0.70

Occipital

− 0.35 ± 4.17 %

0.90

Parietal

0.16 ± 5.44 %

0.72

Lateral temporal

0.77 ±5.44 %

0.63

Anterior cingulate

− 0.90 ± 7.01 %

0.88

Posterior cingulate

− 0.73 ± 7.26 %

0.86

Tau

Mesial temporal

2.53 ± 4.32 %

0.04

Fusiform gyrus

1.85 ± 3.49 %

0.05

Inferior temporal

2.07 ± 3.84 %

0.04

Superior temporal

0.70 ± 2.57 %

0.31

Occipital

1.00 ± 4.76 %

0.28

Parietal

1.75 ± 4.51 %

0.10

  1. SUVR standardize uptake value ratio, p: p-values obtained using linear mixed effect models