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Table 4 Percent amyloid-beta and tau accumulation over 1 year and p-values assessing significant accumulation over time

From: Evaluation of tau deposition using 18F-PI-2620 PET in MCI and early AD subjects—a MissionAD tau sub-study

  Region Percent SUVR change p
Amyloid-beta Frontal 0.46 ± 6.68 % 0.70
Occipital − 0.35 ± 4.17 % 0.90
Parietal 0.16 ± 5.44 % 0.72
Lateral temporal 0.77 ±5.44 % 0.63
Anterior cingulate − 0.90 ± 7.01 % 0.88
Posterior cingulate − 0.73 ± 7.26 % 0.86
Tau Mesial temporal 2.53 ± 4.32 % 0.04
Fusiform gyrus 1.85 ± 3.49 % 0.05
Inferior temporal 2.07 ± 3.84 % 0.04
Superior temporal 0.70 ± 2.57 % 0.31
Occipital 1.00 ± 4.76 % 0.28
Parietal 1.75 ± 4.51 % 0.10
  1. SUVR standardize uptake value ratio, p: p-values obtained using linear mixed effect models