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Table 3 Regional percent of 18F-PI-2620-positive subjects by quantitative assessment (i.e., 18F-PI-2620 SUVR at least two standard deviations above the mean SUVR in healthy controls) in each amyloid-beta group

From: Evaluation of tau deposition using 18F-PI-2620 PET in MCI and early AD subjects—a MissionAD tau sub-study

18F-florbetaben centiloid < 36 36-83 > 83 p
Mesial temporal 0.0% (0/13) 25.8% (8/31) 63.3% (19/30) < 0.0001
Fusiform gyrus 7.7% (1/13) 22.6% (7/31) 53.3% (16/30) 0.001
Inferior temporal 7.7% (1/13) 12.9% (4/31) 50% (15/30) 0.0007
Superior temporal 0.0% (0/13) 6.5% (2/31) 20% (6/30) 0.03
Occipital 0.0% (0/13) 9.7% (3/31) 33.3% (10/30) 0.003
Parietal 7.7% (1/13) 9.7% (3/31) 33.3% (10/30) 0.02
  1. p p-values obtained using the chi-squared test for trend in proportions