Fig. 3From: Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive waysImmune activation in Abi3-Gngt2−/− mice. Representative images of Iba-1 reactive microglia (a–f) and GFAP-reactive astrocyte (g–l) in 3-month-old or 6-month-old mice with WT (+ / +), heterozygous (+ /−), or KO (−/−) of Abi3-Gngt2 genes. Quantitation of the Iba-1 or GFAP staining from cortex or hippocampus is provided in corresponding panels on the right side. N = 6 mice (a–f), 7 mice (g–l). Scale bar, 50 µm. Clear symbols denote female mice and filled symbols denote male mice. Data represents mean ± sem. One-way ANOVA; ***p < 0.001; **p < 0.01; *p < 0.05. KO, knockout; Het, heterozygous; WT, wild typeBack to article page