Fig. 2
From: Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways
ABI3 and GNGT2 genes are in a co-regulatory expression network. a–c Graphs showing co-regulation of ABI3 and GNGT2 RNA from AD patients. Data from Mayo AD cohorts (temporal cortex, TCX and cerebellum, CER) and ROSMAP AD cohorts obtained from AD Knowledge Portal (https://adknowledgeportal.org). d, e Graphs showing co-regulation of Abi3 and Gngt2 RNA from APP TgCRND8 and MAPT rTg4510 mice obtained from AD Knowledge Portal (https://adknowledgeportal.org). f Table depicting the correlation coefficient (ρ) and p-values adjusted for multiple testing for cohorts depicted in a–e. Tg, transgenic for APP (d) or MAPT/tTA (e); nonTg, nontransgenic background strain matched mice (d, e). Each datapoint indicates individual sample (a–e). x and y axes denote FPKM values of ABI3 and GNGT2 respectively