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Table 2 The 15 synaptic proteins and their respective peptides included in the panel. In the far right-hand column, the repeatability (presented as coefficients of variation (CV)) for proteins/peptides quantified in the study is shown. Proteins/peptides marked as bold were included in the statistical analysis

From: Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia

Protein

Accession

Sequence

Position

Repeatability (CV%)

AP-2 complex subunit beta

P63010

NVEGQDMLYQSLK

[880–892]

11.1

IQPGNPNYTLSLK

[905–917]

7.1

Complexin-2

Q6PUV4

AALEQPCEGSLTRPK

[84–98]

15.6

Beta-synuclein

Q16143

EGVVQGVASVAEK

[46–58]

12.3

Gamma-synuclein

O76070

ENVVQSVTSVAEK

[46–58]

8.3

14–3-3 protein eta

Q04917

AVTELNEPLSNEDR

[29–42]

14.7

14–3-3 protein epsilon

P62258

IISSIEQK

[62–69]

21.7

14–3-3 protein zeta/delta

P63104

VVSSIEQK

[61–68]

6.7

Neurogranin

Q92686

KGPGPGGPGGAGVAR

[54–68]

15.0

Rab GDI alpha

P31150

QLICDPSYIPDR

[279–290]

11.7

Syntaxin-1B

P61266

QHSAILAAPNPDEK

[56–69]

16.5

Syntaxin-7

O15400

EFGSLPTTPSEQR

[72–84]

9.3

PEBP-1

P30086

LYEQLSGK

[180–187]

13.5

NRPTSISWDGLDSGK

[48–62]

10.6

Neuronal pentraxin receptor

O95502

NNYMYAR

[302–308]

5.7

LVEAFGGATK

[479–488]

9.5

Neuronal pentraxin-1

Q15818

LENLEQYSR

[144–152]

16.9

CESQSTLDPGAGEAR

[89–103]

6.1

Neuronal pentraxin-2

P47972

VAELEDEK

[177–184]

4.5

WPVETCEER

[419–428]

8.9