Skip to main content
Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: A multiscale brain network model links Alzheimer’s disease-mediated neuronal hyperactivity to large-scale oscillatory slowing

Fig. 5

Normalized average power spectra of simulated MEG across AD-like, healthy control and contrast scenarios. The average power spectra were normalized to total power and averaged over 50 iterations. For each AD-like or contrast scenario, we modified a single model parameter (see Table 2), by increasing (up: shown in red) or decreasing (down: shown in blue) this parameter. Of note, interpretation of the direction (up/down) of parameter modification is intuitively, such that ‘up’ means stronger coupling or hyperexcitability (which is actually derived by lowering the threshold). Control (or healthy) condition is shown in grey. Note that a different y-axis is used for scenario 2B

Back to article page