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Table 4 Influence of regional amyloid deposition on conversion to dementia (ADNI dataset)

From: The impact of subthreshold levels of amyloid deposition on conversion to dementia in patients with amyloid-negative amnestic mild cognitive impairment

  Cutoff SUVR AUC Sensitivity (%) Specificity (%) P value DeLong’s test P value
Bilateral frontal 1.1726 0.582 (0.412–0.753) 63.6 52.8 0.006  
Bilateral parietal 1.2031 0.523 (0.348–0.698) 54.5 50.0 0.006  
Bilateral temporal 1.1257 0.523 (0.348–0.698) 54.5 50.0 0.006  
L) Precuneus 1.244 0.596 (0.426–0.766) 63.6 55.6 0.006  
R) Precuneus 1.2433 0.537 (0.362–0.712) 54.5 52.8 0.006  
L) Posterior cingulate 1.3054 0.537 (0.362–0.712) 54.5 52.8 0.006  
R) Posterior cingulate 1.3244 0.537 (0.362–0.712) 54.5 52.8 0.006  
FBB composite 1.1759 0.582 (0.412–0.753) 52.8 63.6 0.006  
DeLong’s test for the two correlated ROC curves
Model 1
  Bilateral frontal, left precuneus   0.664 (0.487–0.841) 27.3 94.4 < 0.001 0.293
Model 2 (whole VOIs)
  Bilateral frontal, temporal, parietal, posterior cingulate, precuneus, FBB composite   0.732 (0.567–0.893) 72.7 61.1 <0.001