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Table 1 Baseline characteristics of study subjects

From: Hormone therapy and the decreased risk of dementia in women with depression: a population-based cohort study

  Non-dementia group (n = 179,723) Dementia group (n = 29,865) P
Age (years) 61.54 ± 7.83 70.46 ± 6.59 < 0.0001
BMI (kg/m2) 24.26 ± 3.14 24.19 ± 3.31 < 0.001
Systolic BP (mmHg) 125.01 ± 15.81 128.73 ± 16.23 < 0.0001
Diastolic BP (mmHg) 76.63 ± 9.98 77.77 ± 10.08 < 0.0001
Fasting glucose (mg/dL) 99.89 ± 24.24 104.63 ± 30.56 < 0.0001
Total cholesterol (mg/dL) 206.62 ± 46.60 205.47 ± 42.25 < 0.0001
HDL (mg/dL) 57.50 ± 35.39 56.05 ± 35.84 < 0.0001
LDL (mg/dL) 125.28 ± 77.35 123.31 ± 81.84 < 0.0001
Smoking status    0.208
 Never 172,482 (95.97) 28,606 (95.78)  
 Ex-smoker 2121 (1.18) 353 (1.18)  
 Current smoker 5120 (2.85) 906 (3.03)  
Alcohol consumptiona    < 0.0001
 None 160,398 (89.25) 28,075 (94.01)  
 Mild 18,428 (10.25) 1719 (5.76)  
 Heavy 897 (0.50) 71 (0.24)  
Levels of income    < 0.0001
 Medical aid + 1st quartile (the lowest) 37,606 (20.92) 5645 (18.9)  
 2nd quartile 31,760 (17.67) 4842 (16.21)  
 3rd quartile 46,044 (25.62) 6739 (22.56)  
 4th quartile (the highest) 64,313 (35.78) 12,639 (42.32)  
Regular exercise 34,103 (18.98) 3792 (12.70) < 0.0001
Hypertension 90,215 (50.20) 20,248 (67.80) < 0.0001
Diabetes mellitus 26,506 (14.75) 7369 (24.67) < 0.0001
Dyslipidemia 70,467 (39.21) 12,847 (43.02) < 0.0001
Age at menarche (years) 16.50 ± 1.82 16.92 ± 1.79 < 0.0001
Age at menopause (years) 49.99 ± 4.07 49.27 ± 4.56 < 0.0001
Duration of fertility (years) 33.49 ± 4.45 32.35 ± 4.95 < 0.0001
Duration of OC use (years)    < 0.0001
 Never 149,286 (83.06) 26,008 (87.09)  
 < 1 17,771 (9.89) 2156 (7.22)  
 ≥ 1 12,666 (7.05) 1701 (5.70)  
Duration of HRT (years)    < 0.0001
 Never 140,749 (78.31) 26,781 (89.67)  
 < 2 22,097 (12.30) 1735 (5.81)  
 2–5 9182 (5.11) 663 (2.22)  
 ≥ 5 7695 (4.28) 686 (2.30)  
  1. Data are expressed as the mean ± standard deviation, SD, or n (%)
  2. Abbreviations: BMI body mass index, BP blood pressure, HDL high-density lipoprotein, LDL low-density lipoprotein, OC oral contraceptives, HRT hormone replacement therapy
  3. aAlcohol consumption: mild = up to 30 g (equivalent to 3 drinks) a day; heavy = more than 30 g a day