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Table 1 Baseline characteristics of study subjects

From: Hormone therapy and the decreased risk of dementia in women with depression: a population-based cohort study

 

Non-dementia group (n = 179,723)

Dementia group (n = 29,865)

P

Age (years)

61.54 ± 7.83

70.46 ± 6.59

< 0.0001

BMI (kg/m2)

24.26 ± 3.14

24.19 ± 3.31

< 0.001

Systolic BP (mmHg)

125.01 ± 15.81

128.73 ± 16.23

< 0.0001

Diastolic BP (mmHg)

76.63 ± 9.98

77.77 ± 10.08

< 0.0001

Fasting glucose (mg/dL)

99.89 ± 24.24

104.63 ± 30.56

< 0.0001

Total cholesterol (mg/dL)

206.62 ± 46.60

205.47 ± 42.25

< 0.0001

HDL (mg/dL)

57.50 ± 35.39

56.05 ± 35.84

< 0.0001

LDL (mg/dL)

125.28 ± 77.35

123.31 ± 81.84

< 0.0001

Smoking status

  

0.208

 Never

172,482 (95.97)

28,606 (95.78)

 

 Ex-smoker

2121 (1.18)

353 (1.18)

 

 Current smoker

5120 (2.85)

906 (3.03)

 

Alcohol consumptiona

  

< 0.0001

 None

160,398 (89.25)

28,075 (94.01)

 

 Mild

18,428 (10.25)

1719 (5.76)

 

 Heavy

897 (0.50)

71 (0.24)

 

Levels of income

  

< 0.0001

 Medical aid + 1st quartile (the lowest)

37,606 (20.92)

5645 (18.9)

 

 2nd quartile

31,760 (17.67)

4842 (16.21)

 

 3rd quartile

46,044 (25.62)

6739 (22.56)

 

 4th quartile (the highest)

64,313 (35.78)

12,639 (42.32)

 

Regular exercise

34,103 (18.98)

3792 (12.70)

< 0.0001

Hypertension

90,215 (50.20)

20,248 (67.80)

< 0.0001

Diabetes mellitus

26,506 (14.75)

7369 (24.67)

< 0.0001

Dyslipidemia

70,467 (39.21)

12,847 (43.02)

< 0.0001

Age at menarche (years)

16.50 ± 1.82

16.92 ± 1.79

< 0.0001

Age at menopause (years)

49.99 ± 4.07

49.27 ± 4.56

< 0.0001

Duration of fertility (years)

33.49 ± 4.45

32.35 ± 4.95

< 0.0001

Duration of OC use (years)

  

< 0.0001

 Never

149,286 (83.06)

26,008 (87.09)

 

 < 1

17,771 (9.89)

2156 (7.22)

 

 ≥ 1

12,666 (7.05)

1701 (5.70)

 

Duration of HRT (years)

  

< 0.0001

 Never

140,749 (78.31)

26,781 (89.67)

 

 < 2

22,097 (12.30)

1735 (5.81)

 

 2–5

9182 (5.11)

663 (2.22)

 

 ≥ 5

7695 (4.28)

686 (2.30)

 
  1. Data are expressed as the mean ± standard deviation, SD, or n (%)
  2. Abbreviations: BMI body mass index, BP blood pressure, HDL high-density lipoprotein, LDL low-density lipoprotein, OC oral contraceptives, HRT hormone replacement therapy
  3. aAlcohol consumption: mild = up to 30 g (equivalent to 3 drinks) a day; heavy = more than 30 g a day