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Fig. 6 | Alzheimer's Research & Therapy

Fig. 6

From: Near-infrared light reduces β-amyloid-stimulated microglial toxicity and enhances survival of neurons: mechanisms of light therapy for Alzheimer’s disease

Fig. 6

Light effect on the general ROS generation, mitochondrial ROS generation, and ROS in the medium measured for Aβ-treated microglia. Microscope images showing the transmission brightfield, epifluorescence, and merged images of macrophages labeled with CM-H2DCFDA for general ROS detection, MitoSOX™ for mitochondrial ROS detection, and ROS-Glo™ for ROS in the medium. Graphs show the dynamics of ROS generation following stimulation by low-intensity light at 808 nm with 10 J/cm2 during 24 h. The enlarged images are presented in Fig. S6, Supplementary Materials. The data are presented as the mean ± SD (n = 6 replicates in each group); p < 0.05 indicates the data with a statistically significant difference (two-way ANOVA test)

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Alzheimer's Research & Therapy

ISSN: 1758-9193