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Fig. 7 | Alzheimer's Research & Therapy

Fig. 7

From: Longitudinal evaluation of neuroinflammation and oxidative stress in a mouse model of Alzheimer disease using positron emission tomography

Fig. 7

Volume measurements of different regions of interest in 12-month-old 5xFAD and control mice. A 7 consecutive planes (500 µm thickness) of the T2w images acquired for one 5xFAD and one control mice. B Delineation of the regions of interest considered for volumetric analysis, including the three regions that showed significant differences (cortex, CTX; thalamus, THA; and hippocampus, HIP). C Box plots of the normalized volumes (% total brain volume) for the ROIs that presented significant changes in volume at the level of P < 0.05 (*) or P < 0.01 (**) (cortex, CTX; thalamus, THA; and hippocampus, HIP)

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