Fig. 3
From: Plasma neuregulin 1 as a synaptic biomarker in Alzheimer’s disease: a discovery cohort study
Association to CSF synaptic biomarkers and cognition. Association of plasma NRG1 with A CSF GAP-43, B CSF neurogranin, C CSF SNAP-25, and D MMSE, studied using linear regression adjusted on age and sex, in the whole cohort and in regard to Aβ status. Solid lines indicate the regression line and dashed lines, the 95% CI in Aβ-positive and Aβ-negative groups. Abbreviations: Aβ+, amyloid-beta positive; Aβ-, amyloid-beta negative; 95% CI, 95% confidence interval; CSF, cerebrospinal fluid; GAP-43, growth-associated protein 43; MMSE, Mini-Mental State Examination; NRG1, neuregulin 1; SNAP-25, synaptosomal associated protein 25