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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Plasma neuregulin 1 as a synaptic biomarker in Alzheimer’s disease: a discovery cohort study

Fig. 2

Association to AD CSF biomarkers. Association of plasma NRG1 with A CSF NRG1 B CSF Aβ42/Aβ40 ratio, C CSF p-tau, and D CSF t-tau, studied using linear regression adjusted on age and sex, in the whole cohort and in regard to Aβ status. Solid lines indicate the regression line and dashed lines, the 95% CI in Aβ-positive and Aβ-negative groups. Abbreviations: Aβ+, amyloid-beta positive; Aβ-, amyloid-beta negative; Aβ42, β-amyloid 42; Aβ40, β-amyloid 40; AD, Alzheimer’s disease; 95% CI, confidence interval; CSF, cerebrospinal fluid; NRG1, neuregulin 1; p-tau, phosphorylated tau; t-tau, total tau

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