From: The course of primary progressive aphasia diagnosis: a cross-sectional study
PPA (n=5186) | AD (n=162,005) | ||||
---|---|---|---|---|---|
Mean | [SD] | Mean | [SD] | p-value | |
Age when first diagnosed, years | 73.7 | [9.1] | 81.4 | [8.0] | <.001 |
MMSE at ±1 year after diagnosis | 19.5 | [7.3] | 17.9 | [5.9] | <.001 |
n | (%) | n | (%) | p-value | |
Gender | <.001 | ||||
Female | 2887 | (55.7) | 112,751 | (69.6) | |
Male | 2299 | (44.3) | 49,254 | (30.4) | |
Type of centre | <.001 | ||||
Memory clinic | 2739 | (52.8) | 120,750 | (74.5) | |
Regional specialized memory clinic | 2309 | (44.5) | 37,361 | (23.1) | |
Private neurologist | 138 | (2.7) | 3894 | (2.4) | |
Age at first consultation following diagnosis, years | <.001 | ||||
< 50 | 38 | (0.7) | 462 | (0.3) | |
[50, 55[ | 89 | (1.7) | 567 | (0.4) | |
[55, 60[ | 205 | (4.0) | 1493 | (0.9) | |
[60, 65] | 533 | (10.3) | 3038 | (1.9) | |
[65, 70] | 807 | (15.6) | 6694 | (4.1) | |
[70, 75] | 966 | (18.6) | 14,801 | (9.1) | |
[75, 80] | 1191 | (23.0) | 31,774 | (19.6) | |
[80, 85] | 923 | (17.8) | 47,930 | (29.6) | |
≥ 85 | 834 | (8.4) | 55,246 | (34.1) | |
Education | <.001 | ||||
No education | 205 | (4.0) | 12,523 | (7.7) | |
Primary | 1536 | (29.6) | 75,615 | (46.7) | |
Secondary first cycle | 1067 | (20.6) | 26,893 | (16.6) | |
Secondary second cycle | 805 | (15.5) | 14,715 | (9.1) | |
Superior | 1022 | (19.7) | 13,222 | (8.2) | |
Unknown | 551 | (10.6) | 19,037 | (11.8) | |
Initially referred by | <.001 | ||||
General practitioner | 2839 | (54.7) | 106,157 | (65.5) | |
Neurologist | 1152 | (22.2) | 9751 | (6.0) | |
Other specialists | 592 | (11.4) | 17,665 | (10.9) | |
Direct | 233 | (4.5) | 6974 | (4.3) | |
Others | 370 | (7.1) | 21,458 | (13.3) | |
Community-dwelling | <.001 | ||||
No | 333 | (6.4) | 27,240 | (16.8) | |
Yes | 4853 | (93.6) | 134,765 | (83.2) | |
Patient location | <.001 | ||||
Within 50 km from the memory clinic | 4245 | (81.9) | 148,844 | (91.9) | |
Over 50 km from the memory clinic | 941 | (18.2) | 13,161 | (8.1) |