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Table 3 Multivariate analysis including the average of OCT outcomes statistically significant in the univariate analysis

From: The retinal ganglion cell layer reflects neurodegenerative changes in cognitively unimpaired individuals

 

Ratio AB 1 42/40

pTau

tTau

Hippocampal volume

Beta (95%CI)

p-value

Beta (95%CI)

p-value

Beta (95%CI)

p-value

Beta (95%CI)

p-value

AVG BMO-MRW

6.47E−5 (− 2.74E−5 to 15.7E−5)

0.166

− 0.5 (− 0.16 to 0.06)

0.335

− 0.21 (− 0.79 to 0.36)

0.465

1.32 (− 0.16 to 2.80)

0.080

AVG RNFL

8.97E−5 (− 29.6E−5 to 47.6E−5)

0.645

− 0.14 (− 0.57 to 0.29)

0.517

− 1.06 (− 3.36 to 1.23)

0.361

8.91 (3.06 to 14.76)

0.003

AVG GCL

− 0.00 (− 0.001 to 0.001)

0.097

− 0.87 (− 1.89 to 0.16)

0.097

− 4.46 (− 9.99 to 1.06)

0.112

18.04 (3.50 to 32.58)

0.016

  1. Significative values (p < 0.005) are in bold
  2. Abbreviations: BMO-MRW Bruch’s membrane opening-minimum rim width, GCL Ganglion cell layer, I Inferior, N Nasal, RNFL Retinal nerve fiber layer, S Superior, T Temporal